Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sox2  SRY (sex determining region Y)-box 2   (Synonyms: lcc, Sox-2, ysb)
Results	Reference
1	J:275515 Ahmad ST, Rogers AD, Chen MJ, Dixit R, Adnani L, Frankiw LS, Lawn SO, Blough MD, Alshehri M, Wu W, Marra MA, Robbins SM, Cairncross JG, Schuurmans C, Chan JA, Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors. Nat Commun. 2019 May 1;10(1):2000
1	J:177950 Bakircioglu M, Carvalho OP, Khurshid M, Cox JJ, Tuysuz B, Barak T, Yilmaz S, Caglayan O, Dincer A, Nicholas AK, Quarrell O, Springell K, Karbani G, Malik S, Gannon C, Sheridan E, Crosier M, Lisgo SN, Lindsay S, Bilguvar K, Gergely F, Gunel M, Woods CG, The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis. Am J Hum Genet. 2011 May 13;88(5):523-35
1	J:99610 Ekonomou A, Kazanis I, Malas S, Wood H, Alifragis P, Denaxa M, Karagogeos D, Constanti A, Lovell-Badge R, Episkopou V, Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1. PLoS Biol. 2005 Jun;3(6):e186
1	J:149800 Falk S, Wurdak H, Ittner LM, Ille F, Sumara G, Schmid MT, Draganova K, Lang KS, Paratore C, Leveen P, Suter U, Karlsson S, Born W, Ricci R, Gotz M, Sommer L, Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion. Cell Stem Cell. 2008 May 8;2(5):472-83
1	J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489
1*	J:123544 Hume CR, Bratt DL, Oesterle EC, Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns. 2007 Aug;7(7):798-807
1	J:279053 Ito H, Shiwaku H, Yoshida C, Homma H, Luo H, Chen X, Fujita K, Musante L, Fischer U, Frints SG, Romano C, Ikeuchi Y, Shimamura T, Imoto S, Miyano S, Muramatsu SI, Kawauchi T, Hoshino M, Sudol M, Arumughan A, Wanker EE, Rich T, Schwartz C, Matsuzaki F, Bonni A, Kalscheuer VM, Okazawa H, In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells. Mol Psychiatry. 2015 Apr;20(4):459-71
1	J:290262 Kodama Y, Harinath D, Mihara-Tomiyama N, Tominaga N, Ide Y, Nakahara T, Maeda M, Igarashi M, D'Armiento J, Chada K, Imai K, Hmga2 regulation of tooth formation and association with Sox2 and Nanog expression. Biochem Biophys Res Commun. 2019 Feb 19;509(4):1008-1014
1	J:204402 Li C, Ito H, Fujita K, Shiwaku H, Qi Y, Tagawa K, Tamura T, Okazawa H, Sox2 transcriptionally regulates PQBP1, an intellectual disability-microcephaly causative gene, in neural stem progenitor cells. PLoS One. 2013;8(7):e68627
1	J:285766 Lian G, Wong T, Lu J, Hu J, Zhang J, Sheen V, Cytoskeletal Associated Filamin A and RhoA Affect Neural Progenitor Specification During Mitosis. Cereb Cortex. 2019 Mar 1;29(3):1280-1290
1	J:333826 Loan A, Leung JW, Cook DP, Ko C, Vanderhyden BC, Wang J, Chan HM, Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model. iScience. 2023 Mar 17;26(3):106093
1	J:212532 Lv X, Jiang H, Li B, Liang Q, Wang S, Zhao Q, Jiao J, The crucial role of atg5 in cortical neurogenesis during early brain development. Sci Rep. 2014;4:6010
1	J:254987 Mann ZF, Galvez H, Pedreno D, Chen Z, Chrysostomou E, Zak M, Kang M, Canden E, Daudet N, Shaping of inner ear sensory organs through antagonistic interactions between Notch signalling and Lmx1a. Elife. 2017 Dec 4;6:e33323
1	J:147568 Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK, Tassa C, Berry EM, Soda T, Singh KK, Biechele T, Petryshen TL, Moon RT, Haggarty SJ, Tsai LH, Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell. 2009 Mar 20;136(6):1017-31
1	J:296030 Mestres I, Einsiedel M, Moller J, Cardoso de Toledo B, Smad anchor for receptor activation nuclear localization during development identifies Layers V and VI of the neocortex. J Comp Neurol. 2020 Sep 1;528(13):2161-2173
1	J:272577 Mok KW, Saxena N, Heitman N, Grisanti L, Srivastava D, Muraro MJ, Jacob T, Sennett R, Wang Z, Su Y, Yang LM, Ma'ayan A, Ornitz DM, Kasper M, Rendl M, Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent. Dev Cell. 2019 Jan 7;48(1):32-48.e5
1*	J:287342 Nakagawa T, Hattori S, Nobuta R, Kimura R, Nakagawa M, Matsumoto M, Nagasawa Y, Funayama R, Miyakawa T, Inada T, Osumi N, Nakayama KI, Nakayama K, The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression. iScience. 2020 Apr 6;23(4):101030
1	J:234092 Noguchi H, Murao N, Kimura A, Matsuda T, Namihira M, Nakashima K, DNA Methyltransferase 1 Is Indispensable for Development of the Hippocampal Dentate Gyrus. J Neurosci. 2016 Jun 1;36(22):6050-68
1	J:217588 Perdigoto CN, Bardot ES, Valdes VJ, Santoriello FJ, Ezhkova E, Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network. Development. 2014 Dec;141(24):4690-6
1	J:234178 Perdigoto CN, Dauber KL, Bar C, Tsai PC, Valdes VJ, Cohen I, Santoriello FJ, Zhao D, Zheng D, Hsu YC, Ezhkova E, Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet. 2016 Jul;12(7):e1006151
1	J:346066 Rasool D, Burban A, Sharanek A, Madrigal A, Hu J, Yan K, Qu D, Voss AK, Slack RS, Thomas T, Bonni A, Picketts DJ, Soleimani VD, Najafabadi HS, Jahani-Asl A, PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS. EMBO Rep. 2024 Mar;25(3):1256-1281
1	J:258738 Shen T, Ji F, Wang Y, Lei X, Zhang D, Jiao J, Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder. Nucleic Acids Res. 2018 Mar 16;46(5):2290-2307
1	J:318606 Shen T, Ji F, Yuan Z, Jiao J, CHD2 is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex. Stem Cells. 2015 Jun;33(6):1794-806
1	J:286609 Tait CM, Chinnaiya K, Manning E, Murtaza M, Ashton JP, Furley N, Hill CJ, Alves CH, Wijnholds J, Erdmann KS, Furley A, Rashbass P, Das RM, Storey KG, Placzek M, Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal. PLoS Biol. 2020 Mar;18(3):e3000470
1	J:277380 Telley L, Agirman G, Prados J, Amberg N, Fievre S, Oberst P, Bartolini G, Vitali I, Cadilhac C, Hippenmeyer S, Nguyen L, Dayer A, Jabaudon D, Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. Science. 2019 May 10;364(6440)
1	J:191568 Wang Q, Yang L, Alexander C, Temple S, The niche factor syndecan-1 regulates the maintenance and proliferation of neural progenitor cells during mammalian cortical development. PLoS One. 2012;7(8):e42883
1	J:337816 Wang W, Su L, Ji F, Zhang D, Wang Y, Zhao J, Jiao RD, Zhang M, Huang E, Jiang H, Zhang J, Jiao J, The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse. EMBO Rep. 2022 Feb 3;23(3):e53602
1	J:255060 Xia W, Jiao J, Histone variant H3.3 orchestrates neural stem cell differentiation in the developing brain. Cell Death Differ. 2017 Sep;24(9):1548-1563